Journal: Veterinary and Comparative Oncology

Article Title: Diagnostic Evaluation of the Sysmex XN ‐ 1000V Lymphocyte Fluorescence for Differentiating Canine Nodal Large B‐Cell and T‐Cell Lymphoma

doi: 10.1111/vco.70032

Figure Lengend Snippet: New WDF gate in the manual analysis (extended) from the Sysmex XN‐1000V. (A) Large B‐cell lymphoma aspirate with numerous HFC and part of the main cell population outside the scattergram representation area (arrow). (B) Large T‐cell lymphoma aspirate with most of the cells below the HFC gate and exhibiting low fluorescence intensity. HFC, highly fluorescent cells; SFL, side fluorescence light; SSC, side scatter; TC, total cells; WDF, white blood cell differential.

Article Snippet: This study assessed the diagnostic performance of the Sysmex XN‐1000V white blood cell differential (WDF) scattergram to differentiate canine nodal large B‐cell and T‐cell lymphoma, using the percentage of highly fluorescent cells (%HFC) and visual WDF scattergram evaluation.

Techniques: Fluorescence

Journal: Veterinary and Comparative Oncology

Article Title: Diagnostic Evaluation of the Sysmex XN ‐ 1000V Lymphocyte Fluorescence for Differentiating Canine Nodal Large B‐Cell and T‐Cell Lymphoma

doi: 10.1111/vco.70032

Figure Lengend Snippet: Differentiation of canine large B‐cell and T‐cell lymphoma using %HFC calculated on the WDF channel from the Sysmex XN‐1000V. (A) Scatter plot showing the different %HFC in both lymphoma phenotypes. (B) ROC curve for %HFC in distinguishing B‐cell from T‐cell lymphoma in dogs. %HFC, percentage of highly fluorescent cells; ROC, receiver operating characteristic.

Article Snippet: This study assessed the diagnostic performance of the Sysmex XN‐1000V white blood cell differential (WDF) scattergram to differentiate canine nodal large B‐cell and T‐cell lymphoma, using the percentage of highly fluorescent cells (%HFC) and visual WDF scattergram evaluation.

Techniques:

Journal: Materials Today Bio

Article Title: Robust and ultra-stable nanohesive-based solid-like slippery coating under dynamic blood flow environment for durable prevention of thrombosis and biofouling

doi: 10.1016/j.mtbio.2025.102449

Figure Lengend Snippet: Test of antithrombosis properties of SSCMC in vitro and in vivo . a) Surgical schematic of in vitro blood circulation in rabbits. b) Diagrams of blood cells adhering to the inner lumen of both catheters before and after modification of in vitro blood circulation for 2 h. c) Comparison of blood cells adhering to the surfaces of both catheters before and after modification of the inner lumen of both catheters under SEM. d) ∼ f) Quantification of thrombus weight, lumen occlusion and blood flow rate formed in the lumen of the two catheters, respectively. g) Blood circulation modeling to perform blood correlation analysis. h) Thrombin-antithrombin III enzyme complex (TAT) (an early marker of coagulation activation). i) Tissue-type fibrinogen activator-inhibitor 1 complex (PIC) (risk indicator for venous thromboembolism). j) Thrombomodulin (TM). k) Platelets (PLT). l) White blood cells (WBC). m) Serum albumin (ALB). n) Acute inflammation indicator c-reactive protein (CRP). o) Tumor necrosis factor (TNF-α). p) IL-6. q) IL-10. r) Liver function indicator alanine aminotransferase (ALT). s) Kidney function indicator serum creatinine (Scr). Error bar represents the mean ± SD. Significance was calculated by one-way analysis of variance. ∗∗∗∗ p < 0.0001. N = 4, averaged.

Article Snippet: At predetermined time intervals (after 0, 5, 30, and 60 min of circulation), rabbit blood was collected for biochemical analysis, including thrombin-antithrombin complex (TAT, CUSABIO), fibrinolytic-α2 fibrinolytic inhibitor complex (PIC, mlbio), thrombomodulin (TM, mlbio), platelet (PLT), white blood cell (WBC), serum albumin (ALB, proteintech), C-reactive protein (CRP, proteintech), tumor necrosis factor-α (TNF-α, proteintech), and inflammatory and immunosuppressive factors (IL-6, IL-10, proteintech) to assess physiological parameters such as coagulation, inflammatory response, and organ function.

Techniques: In Vitro, In Vivo, Modification, Comparison, Marker, Coagulation, Activation Assay